Question:

The configuration at C-8 and C-9 position of quinine is:

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Quinine (Levo) = 8S, 9R; Quinidine (Dextro) = 8R, 9S.
Updated On: May 15, 2026
  • 8R,9S
  • 8S,9R
  • 9S,8S
  • 9R,8R
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The Correct Option is B

Solution and Explanation


Step 1: Concept

Quinine and Quinidine are diastereomers found in Cinchona bark, differing in their stereochemistry.

Step 2: Meaning

Configuration is assigned using the Cahn-Ingold-Prelog (CIP) priority rules.

Step 3: Analysis

Quinine has the (8S, 9R) configuration. Its diastereomer, Quinidine, has the (8R, 9S) configuration.

Step 4: Conclusion

The specific configuration for Quinine at the 8 and 9 positions is 8S and 9R. Final Answer: (B)
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