Question:

Study the following statements regarding muscle and identify incorrect statements.
A) In mammals the sarcolemma penetrate between A and I bands to form T-tubule.
B) Tetanus is caused due to accumulation of uric acid crystals.
C) Troponin is distributed at regular intervals on tropomyosin.
D) White muscle fibres have more mitochondria and depends on anaerobiosis.

Show Hint

Do not confuse physiological tetanus (sustained contraction) or the infection Tetanus with Gout (uric acid deposition).
Red fibers = high myoglobin, high mitochondria, aerobic.
White fibers = low myoglobin, low mitochondria, anaerobic.
Updated On: Jul 22, 2026
  • A & C
  • B & C
  • B & D
  • A & D
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Question:
We need to analyze four anatomical and physiological statements regarding muscular structure, types, and disorders to identify which ones are incorrect.

Step 2: Key Concept and Approach:
We will review each statement systematically:
- T-tubules are invaginations of the sarcolemma.
- Tetanus is characterized by rapid spasm/sustained contraction, whereas uric acid accumulation causes gout.
- Troponin is a complex on tropomyosin regulating actin-myosin binding.
- White muscle fibers are specialized for anaerobic work but have fewer mitochondria.

Step 3: Detailed Explanation:

Statement A: In mammalian skeletal muscle, transverse tubules (T-tubules) are invaginations of the sarcolemma located specifically at the junction of the A and I bands.
This is correct.

Statement B: Tetanus is a state of sustained muscle contraction caused by high-frequency motor stimuli or by the toxin of Clostridium tetani.
Accumulation of uric acid crystals in joints causes gout, not tetanus.
Thus, Statement B is incorrect.

Statement C: Troponin is a complex of regulatory proteins distributed at regular intervals along the tropomyosin filaments.
This is correct.

Statement D: White muscle fibers contain less myoglobin and fewer mitochondria compared to red muscle fibers.
While they do rely on anaerobic respiration (anaerobiosis), they do not have "more mitochondria."
Thus, Statement D is incorrect.

• Therefore, statements B and D are the incorrect statements.


Step 4: Final Answer:
The incorrect statements are B and D, making Option (C) the correct choice.
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