Question:
Sterile pyuria is present in:
Sterile pyuria is present in:
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Think of an organism that won't grow on routine urine culture.
Updated On: Jun 24, 2026
- Renal tuberculosis
- Chronic hydronephrosis
- Wilms' tumour
- Neuroblastoma
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The Correct Option is A
Solution and Explanation
Step 1: Sterile pyuria means pus cells (leukocytes) are present in the urine but routine bacterial culture is negative.
Step 2: A classic cause is renal (genitourinary) tuberculosis, because Mycobacterium tuberculosis does not grow on ordinary culture media used for routine urine culture, yet it causes an inflammatory pyuria.
Step 3: Chronic hydronephrosis is obstructive dilatation of the collecting system and does not by itself cause sterile pyuria, so option B is not the best answer.
Step 4: Wilms' tumour (nephroblastoma) and neuroblastoma are paediatric solid tumours that present with an abdominal mass and possibly haematuria, not with sterile pyuria, so options C and D are wrong.
Conclusion: The correct answer is option 1, renal tuberculosis, matching the printed key.
Step 2: A classic cause is renal (genitourinary) tuberculosis, because Mycobacterium tuberculosis does not grow on ordinary culture media used for routine urine culture, yet it causes an inflammatory pyuria.
Step 3: Chronic hydronephrosis is obstructive dilatation of the collecting system and does not by itself cause sterile pyuria, so option B is not the best answer.
Step 4: Wilms' tumour (nephroblastoma) and neuroblastoma are paediatric solid tumours that present with an abdominal mass and possibly haematuria, not with sterile pyuria, so options C and D are wrong.
Conclusion: The correct answer is option 1, renal tuberculosis, matching the printed key.
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