Question:

Selenocysteine is associated with which of the following?

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Think of the selenoenzyme that converts T4 to T3.
Updated On: Jun 24, 2026
  • Carbonic anhydrase
  • Catalase
  • Deiodinase
  • Transferase
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The Correct Option is C

Solution and Explanation

Step 1: Selenocysteine is regarded as the 21st amino acid. It is structurally like cysteine but has selenium in place of the sulfur atom, and it sits at the active site of certain redox enzymes.

Step 2: The selenoenzymes that use a selenocysteine residue include glutathione peroxidase, thioredoxin reductase and the iodothyronine deiodinases, which convert thyroxine (T4) to the active triiodothyronine (T3).

Step 3: Among the options, only deiodinase is a selenocysteine-containing enzyme, so option 3 is correct.

Step 4: Carbonic anhydrase is a zinc enzyme, catalase is a heme (iron) enzyme, and transferase is a generic enzyme class that does not require selenocysteine. Hence options 1, 2 and 4 are wrong.
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