Retroviruses are commonly used in gene therapy and can be engineered to deliver approximately 8000 bases of single-stranded RNA. This RNA is reverse-transcribed into DNA, which integrates into the host genome, enabling stable expression of therapeutic genes.
| List I (Enzyme) | List II (Function) |
|---|---|
| (A) Cytochrome oxidase | (I) Electron transport system |
| (B) Topoisomerases | (II) Change linking number |
| (C) Cohesins | (III) DNA Replication |
| (D) PCNA | (IV) Cell cycle |