Question:
Prolactin is secreted maximally at:
Prolactin is secreted maximally at:
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Think of when the breast needs the most prolactin to start milk.
Updated On: Jun 23, 2026
- 24 hours after delivery
- REM sleep
- 2 hours of running
- 24 hours after ovulation
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The Correct Option is A
Solution and Explanation
Step 1: Among the given choices, prolactin reaches its maximum level 24 hours after delivery.
Step 2: After delivery, the sudden fall in estrogen and progesterone releases the lactotrophs from inhibition, and prolactin surges to support lactation.
Step 3: Prolactin also rises with strenuous exercise and with sleep, but the sleep-related rise is during NREM (deep) sleep, not REM, so option 2 is wrong. The exercise rise is real but far smaller than the postpartum surge.
Step 4: About 24 hours after ovulation, estrogen exerts negative feedback that lowers prolactin, so option 4 is incorrect.
So the correct answer is 24 hours after delivery.
Step 2: After delivery, the sudden fall in estrogen and progesterone releases the lactotrophs from inhibition, and prolactin surges to support lactation.
Step 3: Prolactin also rises with strenuous exercise and with sleep, but the sleep-related rise is during NREM (deep) sleep, not REM, so option 2 is wrong. The exercise rise is real but far smaller than the postpartum surge.
Step 4: About 24 hours after ovulation, estrogen exerts negative feedback that lowers prolactin, so option 4 is incorrect.
So the correct answer is 24 hours after delivery.
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