Question:

Oxygen therapy may NOT be useful (and may be harmful) in:

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Oxygen worsens oxidative lung injury states.
Updated On: Jun 24, 2026
  • Asthma
  • Pneumonia
  • Subglottic stenosis
  • Pulmonary fibrosis
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The Correct Option is D

Solution and Explanation

Step 1: Although many protocols say oxygen should not be withheld from any patient, certain situations are known to do harm with oxygen therapy.

Step 2: These include paraquat poisoning, pulmonary fibrosis, and lung damage from bleomycin treatment, where high oxygen tension can worsen oxidative lung injury. So pulmonary fibrosis (option 4) is the answer.

Step 3: In asthma and pneumonia, supplemental oxygen relieves hypoxaemia and is clearly beneficial, and in subglottic stenosis oxygen supports gas exchange while the airway obstruction is addressed.

Step 4: Therefore the condition where oxygen may not be useful, and can be detrimental, is pulmonary fibrosis.
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