Question:

On day 21 of a 28-day menstrual cycle, which hormone profile is correct?

Show Hint

Day 21 = luteal phase = high progesterone with suppressed FSH and LH.
Updated On: May 14, 2026
  • $\uparrow P, \uparrow E, \downarrow FSH, \downarrow LH$
  • $\uparrow P, \downarrow E, \downarrow FSH, \downarrow LH$
  • $\downarrow P, \downarrow E, \uparrow LH, \uparrow FSH$
  • $\uparrow E, \downarrow P, \uparrow LH, \downarrow FSH$
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The Correct Option is B

Solution and Explanation

Concept: Day 21 of a 28-day cycle lies in the luteal phase. In the luteal phase, the corpus luteum secretes progesterone. FSH and LH are suppressed by negative feedback.

Step 1:
Identify the phase.
Ovulation occurs around day 14. Day 21 is after ovulation, so it is the: \[ \text{Luteal phase} \]

Step 2:
Identify the dominant hormone.
The corpus luteum produces progesterone: \[ P \uparrow \]

Step 3:
Understand feedback effect.
Progesterone suppresses pituitary gonadotropins: \[ FSH \downarrow, \quad LH \downarrow \] Among the given options, the best matching profile is: \[ \uparrow P, \downarrow E, \downarrow FSH, \downarrow LH \] Therefore, the correct answer is Option B.
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