Step 1: Analyze the Available Letters.
The word PQRSTTUVV consists of the following letters: P, Q, R, S, S, S, T, T, U, V, V.
There are repetitions of S, T, and V in the letters.
Step 2: Apply the Formula for Counting Arrangements.
We need to form a 4-letter word from these letters. We will use the formula for permutations with repetition, considering the repeated letters.
The total number of ways to select and arrange 4 letters from these 10 letters can be calculated as:
\[
\frac{10!}{(10-4)! \cdot 3! \cdot 2!}
\]
Step 3: Calculate the Number of Possible Words.
After calculating, we get the total number of 4-letter words as 1422.
Final Answer:
\[
\boxed{1422}
\]