Question:

Neisseria gonorrhoeae pili bind to which receptor:

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Gonorrhoeae + Pili $\rightarrow$ CD46.
Updated On: May 25, 2026
  • CD14
  • CD
  • CD46
  • CD4
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The Correct Option is C

Solution and Explanation

Step 1: Concept
Pili (fimbriae) are hair-like appendages on the bacterial surface that mediate attachment to host cells.

Step 2: Meaning

Adhesion is a crucial first step in the pathogenesis of Neisseria gonorrhoeae.

Step 3: Analysis

The Type IV pili of the gonococcus specifically recognize and bind to CD46 (Membrane Cofactor Protein) on human epithelial cells.

Step 4: Conclusion

Binding to CD46 allows the bacteria to colonize the host mucosal surfaces. Final Answer: (C)
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