Question:
Mendelian Disorders
Read the following passage carefully and answer the given questions.
Genetic disorders may be grouped into two categories - Mendelian disorders and Chromosomal disorders. Mendelian disorders are mainly determined by alteration or mutation in a single gene. These disorders are transmitted to the offspring on the same lines as in the principle of inheritance. The pattern of inheritance of such Mendelian disorders can be traced in a family by pedigree analysis. Most common and prevalent Mendelian disorders are Haemophilia, Cystic fibrosis, Sickle-cell anaemia, Colour blindness, Phenylketonuria, Thalassemia, etc. The Mendelian disorders may be dominant or recessive. By pedigree analysis, one can easily understand whether the trait in question is dominant or recessive. Similarly, the trait may also be linked to the sex chromosome or an autosome.
\(\alpha\)-thalassemia is controlled by the genes:
Mendelian Disorders
Read the following passage carefully and answer the given questions.
Genetic disorders may be grouped into two categories - Mendelian disorders and Chromosomal disorders. Mendelian disorders are mainly determined by alteration or mutation in a single gene. These disorders are transmitted to the offspring on the same lines as in the principle of inheritance. The pattern of inheritance of such Mendelian disorders can be traced in a family by pedigree analysis. Most common and prevalent Mendelian disorders are Haemophilia, Cystic fibrosis, Sickle-cell anaemia, Colour blindness, Phenylketonuria, Thalassemia, etc. The Mendelian disorders may be dominant or recessive. By pedigree analysis, one can easily understand whether the trait in question is dominant or recessive. Similarly, the trait may also be linked to the sex chromosome or an autosome.
\(\alpha\)-thalassemia is controlled by the genes:
Read the following passage carefully and answer the given questions.
Genetic disorders may be grouped into two categories - Mendelian disorders and Chromosomal disorders. Mendelian disorders are mainly determined by alteration or mutation in a single gene. These disorders are transmitted to the offspring on the same lines as in the principle of inheritance. The pattern of inheritance of such Mendelian disorders can be traced in a family by pedigree analysis. Most common and prevalent Mendelian disorders are Haemophilia, Cystic fibrosis, Sickle-cell anaemia, Colour blindness, Phenylketonuria, Thalassemia, etc. The Mendelian disorders may be dominant or recessive. By pedigree analysis, one can easily understand whether the trait in question is dominant or recessive. Similarly, the trait may also be linked to the sex chromosome or an autosome.
\(\alpha\)-thalassemia is controlled by the genes:
Show Hint
Alpha chain genes are on chromosome 16 and beta chain gene is on chromosome 11.
Updated On: Oct 1, 2026
- HBB and HB1 on chromosome 11 of each parent
- HAA1 and HAB1 on chromosome 16 of each parent
- HBA1 and HBA2 on chromosome 16 of each parent
- HBB and HAA on chromosome 11 of each parent
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Thalassemia is a blood disease in which the synthesis of one globin chain of haemoglobin is reduced. In alpha thalassemia the alpha globin chain is affected. In beta thalassemia the beta globin chain is affected.
Step 2: Recall the genes:
Alpha globin is coded by two closely linked genes, HBA1 and HBA2, on chromosome 16. Each parent gives one copy of the pair, so a person has four alpha globin genes. Beta globin is coded by the HBB gene on chromosome 11.
Step 3: Check the options:
Option 1 and option 4 mention chromosome 11 and HBB, which belong to beta thalassemia. Option 2 uses gene names that do not exist. Option 3 gives HBA1 and HBA2 on chromosome 16 and is right.
Final Answer:
Alpha thalassemia is controlled by HBA1 and HBA2 on chromosome 16, which is option 3.
Thalassemia is a blood disease in which the synthesis of one globin chain of haemoglobin is reduced. In alpha thalassemia the alpha globin chain is affected. In beta thalassemia the beta globin chain is affected.
Step 2: Recall the genes:
Alpha globin is coded by two closely linked genes, HBA1 and HBA2, on chromosome 16. Each parent gives one copy of the pair, so a person has four alpha globin genes. Beta globin is coded by the HBB gene on chromosome 11.
Step 3: Check the options:
Option 1 and option 4 mention chromosome 11 and HBB, which belong to beta thalassemia. Option 2 uses gene names that do not exist. Option 3 gives HBA1 and HBA2 on chromosome 16 and is right.
Final Answer:
Alpha thalassemia is controlled by HBA1 and HBA2 on chromosome 16, which is option 3.
Was this answer helpful?
0
0
Top CUET Biology Questions
Select the statements that are CORRECT regarding patterns of biodiversity.
(A) Species diversity increases as we move away from the equator towards the poles(B) The tropical Amazon rain forest in South America has the greatest biodiversity on earth.(C) There is more solar energy available in the temperate region than tropics.(D) Tropical environments are less seasonal relatively more constant and predictableWhich of the following hormone is not produced by placenta ?
- Individuals with karyotype of 44+XXY having overall masculine development with few feminine development like Gynaecomastia has _______ chromosomal disorder.
- Match List - I with List - II.Choose the correct answer from the options given below :
List - I
List - II
A Streptokinase I Blood-Cholestrol lowering agents B Cyclosporin II Clot Buster C Statins III Propionibacterium sharmanii D Swiss Cheese IV Immuno suppressive agent Which of the following option determines percolation and water holding capacity of soils ?
View More Questions
Top CUET Genetics Questions
- Select the correctly matched pair about sickle cell anaemia:
Genotype: Phenotype
(A) HbA HbA : Diseased phenotype
(B) HbA HbS: Diseased phenotype
(C) HbS HbS: Diseased phenotype
(D) HbS HbA : Carrier of disease
Choose the correct answer from the options given below: If a heterozygous tall plant (Tt) is crossed with a dwarf plant (tt), what will be the phenotypic ratio of the offspring?
- Match List I with List II \[ \begin{array}{|l|l|} \hline \textbf{List I} & \textbf{List II} \\ \hline (A) \; \text{Flower Colour} & (I) \; \text{Green} \\ \hline (B) \; \text{Seed colour} & (II) \; \text{Yellow} \\ \hline (C) \; \text{Pod colour} & (III) \; \text{Constricted} \\ \hline (D) \; \text{Pod shape} & (IV) \; \text{White} \\ \hline \end{array} \]
- Which of the following disorders are the results of aneuploidy? (A) Haemophilia
(B) Down’s Syndrome
(C) Thalassemia
(D) Turner’s Syndrome
- Which one of the following options will express intermediate skin colour in an individual?
View More Questions
Top CUET Questions
Select the statements that are CORRECT regarding patterns of biodiversity.
(A) Species diversity increases as we move away from the equator towards the poles(B) The tropical Amazon rain forest in South America has the greatest biodiversity on earth.(C) There is more solar energy available in the temperate region than tropics.(D) Tropical environments are less seasonal relatively more constant and predictableWhich of the following hormone is not produced by placenta ?
- Individuals with karyotype of 44+XXY having overall masculine development with few feminine development like Gynaecomastia has _______ chromosomal disorder.
- Match List - I with List - II.Choose the correct answer from the options given below :
List - I
List - II
A Streptokinase I Blood-Cholestrol lowering agents B Cyclosporin II Clot Buster C Statins III Propionibacterium sharmanii D Swiss Cheese IV Immuno suppressive agent Which of the following option determines percolation and water holding capacity of soils ?
View More Questions