Question

Match the syndromes listed in Column I with the cause/symptoms listed in Column II. 

• A. P–(ii); Q–(v); R–(iv); S–(iii); T–(i)
• B. P–(iv); Q–(iii); R–(i); S–(ii); T–(v)
• C. P–(iii); Q–(iv); R–(i); S–(v); T–(ii)
• D. P–(v); Q–(iv); R–(ii); S–(i); T–(iii)

Hint:

Always link syndromes to either a {chromosomal abnormality} (Down, Turner, Prader-Willi) or a {hormonal/metabolic cause} (Cushing, Fanconi). This helps eliminate distractors quickly.

Answer 1

The Correct Option is C

Step 1: Match each syndrome with its defining cause/symptom.
- Prader-Willi syndrome: Caused by deletion on chromosome 15 $⇒$ (iii).
- Down syndrome: Trisomy 21 (third copy of chromosome 21) $⇒$ (iv).
- Cushing syndrome: Excess cortisol (endogenous or exogenous) $⇒$ (i).
- Turner syndrome: Female missing all or part of an X chromosome $⇒$ (v).
- Fanconi syndrome: Proximal renal tubule reabsorption defect $⇒$ (ii).
Step 2: Compile the matches.
P–(iii), Q–(iv), R–(i), S–(v), T–(ii). Therefore, the correct answer is (C).