Question

Match the inhibitors in Group 1 with their respective targets in Group 2. 
 

• A. ( {P - i, Q - ii, R - iii, S - iv} )
• B. ( {P - iv, Q - i, R - ii, S - iii} )
• C. ( {P - iii, Q - i, R - iv, S - ii} )
• D. ( {P - iv, Q - ii, R - i, S - iii} )

Hint:

Understanding the specific targets of inhibitors is essential in biochemistry for studying metabolic pathways and designing therapeutic strategies.

Answer 1

The Correct Option is B

The correct matching of inhibitors in Group 1 with their respective targets in Group 2 is as follows: 
- P - Oligomycin (iv): Oligomycin inhibits ( F_0 ) ATP synthase by blocking the proton channel, preventing ATP synthesis. 
- Q - Antimycin A (i): Antimycin A inhibits the cytochrome ( bc_1 ) complex in the mitochondrial electron transport chain. 
- R - DCMU (ii): DCMU (3-(3,4-dichlorophenyl)-1,1-dimethylurea) inhibits Photosystem II in the photosynthetic electron transport chain, blocking electron flow. 
- S - Valinomycin (iii): Valinomycin acts as a ( K^+ ) ionophore, facilitating the transport of ( K^+ ) ions across membranes. Thus, the correct answer is ( {P - iv, Q - i, R - ii, S - iii} ), which corresponds to option (B).