Question

Match the following:

• A. \(A-II,\; B-IV,\; C-II,\; D-I\)
• B. \(A-I,\; B-IV,\; C-III,\; D-II\)
• C. \(A-IV,\; B-I,\; C-III,\; D-II\)
• D. \(A-IV,\; B-I,\; C-II,\; D-III\)

Hint:

Remember the sequence: Pyruvate \(\rightarrow\) Acetyl Co-A \(\rightarrow\) Citrate \(\rightarrow\) \(\alpha\)-Ketoglutarate \(\rightarrow\) Succinyl Co-A Acetyl Co-A starts condensation, while Succinyl Co-A participates in substrate level phosphorylation.

Answer 1

The Correct Option is C

Concept: In aerobic respiration and Krebs cycle, different intermediates perform specific metabolic functions.
• Acetyl Co-A combines with oxaloacetic acid to form citric acid.
• Succinyl Co-A participates in substrate level phosphorylation.
• Pyruvic acid is produced at the end of glycolysis.
• \(\alpha\)-Ketoglutaric acid undergoes oxidative decarboxylation.

Step 1: Identify Acetyl Co-A. Acetyl Co-A combines with oxaloacetate during the first condensation reaction of Krebs cycle. \[ B \rightarrow I \]

Step 2: Identify Succinyl Co-A. Succinyl Co-A is the substrate that produces ATP/GTP through substrate level phosphorylation. \[ A \rightarrow IV \]

Step 3: Identify Pyruvic acid. Pyruvic acid is the end product of glycolysis and is therefore considered the product associated with substrate level phosphorylation. \[ C \rightarrow III \]

Step 4: Identify \(\alpha\)-Ketoglutaric acid. \(\alpha\)-Ketoglutarate undergoes oxidative decarboxylation to form succinyl Co-A. \[ D \rightarrow II \] Thus, \[ A-IV,\quad B-I,\quad C-III,\quad D-II \] Hence, option \((C)\) is correct.