Question

Match List I with List II \[ \renewcommand{\arraystretch}{1.5} \begin{array}{|c|l|c|l|} \hline \multicolumn{2}{|c|}{List I & \multicolumn{2}{c|}{List II \hline (a) & \text{Mucus lining} & (I) & \text{Physiological barrier} \hline (b) & \text{Acid in stomach} & (II) & \text{Cellular barrier} \hline (c) & \text{PMNL-neutrophils} & (III) & \text{Physical barrier} \hline (d) & \text{Interferons} & (IV) & \text{Cytokine barrier} \hline \end{array} \] Choose the correct answer from the options given below:

• A. a-II, b-I, c-IV, d-III
• B. a-III, b-II, c-IV, d-I
• C. a-II, b-III, c-I, d-IV
• D. a-III, b-I, c-II, d-IV

Hint:

Innate immunity consists of four major barriers: \[ \text{Physical barrier} \rightarrow \text{Skin, mucus lining} \] \[ \text{Physiological barrier} \rightarrow \text{Stomach acid, saliva} \] \[ \text{Cellular barrier} \rightarrow \text{Neutrophils, macrophages} \] \[ \text{Cytokine barrier} \rightarrow \text{Interferons} \]

Answer 1

The Correct Option is D

Step 1: Match mucus lining. Mucus lining prevents the entry of pathogens into the body. Therefore: \[ (a)\rightarrow(III) \] \[ \text{Mucus lining} \rightarrow \text{Physical barrier} \]

Step 2: Match acid in stomach. Hydrochloric acid present in the stomach destroys many microorganisms. Therefore: \[ (b)\rightarrow(I) \] \[ \text{Acid in stomach} \rightarrow \text{Physiological barrier} \]

Step 3: Match PMNL-neutrophils. PMNL-neutrophils are phagocytic white blood cells. Therefore: \[ (c)\rightarrow(II) \] \[ \text{PMNL-neutrophils} \rightarrow \text{Cellular barrier} \]

Step 4: Match interferons. Interferons are cytokines produced against viral infections. Therefore: \[ (d)\rightarrow(IV) \] \[ \text{Interferons} \rightarrow \text{Cytokine barrier} \] Thus, \[ \boxed{a\text{-III},\; b\text{-I},\; c\text{-II},\; d\text{-IV}} \] Hence, the correct answer is: \[ \boxed{\text{(D)}} \]