Question

Match List-I with List-II:

List-I	List-II
A. Genetically engineered Human Insulin	I. Gene therapy
B. GM Cotton	II. E. coli
C. ADA Deficiency	III. Antigen-antibody interaction
D. ELISA	IV. Bacillus thuringiensis

Choose the correct answer from the options given below:

• A. A-III, B-II, C-IV, D-I
• B. A-II, B-I, C-IV, D-III
• C. A-IV, B-III, C-I, D-II
• D. A-II, B-IV, C-I, D-III

Answer 1

The Correct Option is D

To match List-I with List-II, we need to understand the applications and associations of each item listed under List-I and how they relate to those in List-II. Let's evaluate each pair:

1. Genetically engineered Human Insulin: Insulin is produced by genetically modified bacteria, most commonly E. coli, using recombinant DNA technology. This allows for the commercial production of human insulin in large quantities for diabetic patients.
2. GM Cotton: Genetically modified cotton is often engineered to include a gene from Bacillus thuringiensis (Bt). This bacterium produces a protein that is toxic to certain insect pests, providing the cotton with built-in pest resistance.
3. ADA Deficiency: ADA (Adenosine deaminase) deficiency is often treated using gene therapy. This involves introducing a functional gene into a patient's cells to treat or prevent disease.
4. ELISA: The Enzyme-Linked Immunosorbent Assay (ELISA) is a test that uses antigen-antibody interaction to detect the presence of antigens or antibodies in a sample.

Based on these explanations, we can match the lists as follows:

• A. Genetically engineered Human Insulin - II. E. coli
• B. GM Cotton - IV. Bacillus thuringiensis
• C. ADA Deficiency - I. Gene therapy
• D. ELISA - III. Antigen-antibody interaction

Thus, the correct answer is: A-II, B-IV, C-I, D-III.