Question

Match List I with List II \begin{table}[h] \centering \begin{tabular}{|c|l|c|l|} \hline \multicolumn{2}{|c|}{List I (Drug)} & \multicolumn{2}{c|}{List II (Effect)}
\hline A & Nicotine & I & Causes sense of euphoria and increased energy
B & Morphine & II & Stimulates adrenal gland to release catecholamines into blood circulation
C & Heroin & III & Effective sedative and painkiller
D & Cocaine & IV & A depressant, slows down body function
\hline \end{tabular} \end{table} Choose the correct answer from the options given below:

• A. A-II, B-III, C-IV, D-I
• B. A-III, B-II, C-I, D-IV
• C. A-III, B-II, C-IV, D-I
• D. A-II, B-III, C-I, D-IV

Hint:

Logic Tip: Differentiate between the opiates! While Morphine is actively used in medicine as a "painkiller" (III), its derivative Heroin is highly abused and generally known as a severe "depressant" (IV) that slows body functions.

Answer 1

The Correct Option is A

Concept:
Different classes of drugs and psychoactive substances interact with specific receptors in the human central nervous system (CNS) and endocrine system, producing distinct physiological and psychological effects.
Step 1:
Nicotine (an alkaloid found in tobacco) stimulates the adrenal glands to release adrenaline and noradrenaline (catecholamines) into the bloodstream, which raises blood pressure and heart rate. Match: A $\rightarrow$ II
Step 2:
Morphine is a potent opiate analgesic extracted from the latex of the poppy plant (Papaver somniferum). It acts on specific opioid receptors in the CNS and gastrointestinal tract and is widely used clinically as a very effective sedative and painkiller. Match: B $\rightarrow$ III
Step 3:
Heroin (chemically diacetylmorphine) is synthesized by the acetylation of morphine. It is a powerful CNS depressant that generally slows down body functions. Match: C $\rightarrow$ IV
Step 4:
Cocaine (extracted from the coca plant, Erythroxylum coca) interferes with the transport of the neurotransmitter dopamine. It has a potent stimulating action on the CNS, producing a profound sense of euphoria and a burst of increased energy. Match: D $\rightarrow$ I
Step 5:
Combining the matches yields A-II, B-III, C-IV, D-I, which corresponds perfectly to Option (1).