Question:
LEOPARD syndrome includes all except:
LEOPARD syndrome includes all except:
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The A in LEOPARD is abnormal genitalia (hypogonadism), not hypergonadism.
Updated On: Jun 24, 2026
- Growth retardation
- ECG changes
- Hypertelorism
- Hypergonadism
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The Correct Option is D
Solution and Explanation
Step 1: LEOPARD syndrome is a multisystem disorder whose name is an acronym for its main features. The question asks which listed feature is NOT part of it.
Step 2: Expanding the acronym: L = Lentigines, E = Electrocardiographic conduction abnormalities, O = Ocular hypertelorism, P = Pulmonary stenosis, A = Abnormal genitalia, R = Retarded growth, D = Deafness (sensorineural).
Step 3: Matching the options: growth retardation is the R, ECG changes are the E, and hypertelorism is the O. All three are genuine components.
Step 4: The A in LEOPARD stands for abnormal genitalia, which in fact reflects hypogonadism, not hypergonadism. Therefore hypergonadism is the feature that does NOT belong, so option d is the exception and the correct answer.
Step 2: Expanding the acronym: L = Lentigines, E = Electrocardiographic conduction abnormalities, O = Ocular hypertelorism, P = Pulmonary stenosis, A = Abnormal genitalia, R = Retarded growth, D = Deafness (sensorineural).
Step 3: Matching the options: growth retardation is the R, ECG changes are the E, and hypertelorism is the O. All three are genuine components.
Step 4: The A in LEOPARD stands for abnormal genitalia, which in fact reflects hypogonadism, not hypergonadism. Therefore hypergonadism is the feature that does NOT belong, so option d is the exception and the correct answer.
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