Question:
In which of the following the pyrophosphate bond of ATP is broken down and linkage takes place between two molecules?
In which of the following the pyrophosphate bond of ATP is broken down and linkage takes place between two molecules?
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Ligases are also known as synthetases and are involved in condensation reactions that require energy input from ATP.
Updated On: Apr 16, 2026
- Isomerases
- Lyases
- Transferases
- Ligases
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Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
This question is about enzyme classification and their functions, specifically those involved in ATP-dependent bond formation.
Step 2: Detailed Explanation:
• (A) Isomerases: Catalyze the rearrangement of atoms within a molecule (isomerization). • (B) Lyases: Catalyze the addition or removal of groups to form double bonds, often without ATP. • (C) Transferases: Catalyze the transfer of a functional group from one molecule to another. • (D) Ligases: Catalyze the joining of two molecules, often with the concomitant hydrolysis of a pyrophosphate bond in ATP (or another nucleoside triphosphate). They are involved in DNA replication (DNA ligase) and other biosynthetic reactions.
Step 3: Final Answer:
Ligases break the pyrophosphate bond of ATP to join two molecules, which corresponds to option (D).
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