Question:

In the Tessari technique, what is the ratio of mixing sclerosant to air?

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Tessari technique memory trick: 1 liquid + 4 air = 5 total parts to make a stable Foam.
Always use a three-way stopcock to mix.
Updated On: Sep 3, 2026
  • 1:4
  • 4:1
  • 1:1
  • 1:2
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The Correct Option is A

Solution and Explanation

Concept:
The question tests the precise technical methodology used during foam sclerotherapy for the treatment of varicose veins.
The clinician must recall the universally standardized ratio for creating a stable sclerosant foam.
Explanation:
• Sclerotherapy involves injecting a chemical irritant (sclerosant) into a diseased vein to cause endothelial damage, thrombosis, and eventual fibrosis of the vessel.

• Using the sclerosant as a foam, rather than a liquid, is highly advantageous because the foam displaces blood inside the vein, allowing for maximum, undiluted contact between the chemical and the venous endothelium.

• The Tessari technique is the gold standard method for generating this microfoam.

• It utilizes two syringes connected by a three-way stopcock.

• The universally accepted and proven formula to create the most stable, effective foam with optimal bubble size is mixing 1 part of liquid sclerosant (such as Sodium Tetradecyl Sulfate or Polidocanol) with 4 parts of air (or physiological gas like CO2/O2).

• By vigorously pumping the mixture back and forth between the syringes at this exact 1:4 ratio, a dense, shaving-cream-like microfoam is produced.

• Ratios like 1:1 or 1:2 create a runny, unstable mixture that degrades back to liquid too rapidly in the bloodstream.
Final Answer:
The standard ratio used in the Tessari technique for creating sclerosant foam is 1 part sclerosant to 4 parts air.
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