Question:
In mammals, females have two X chromosomes and males have one X chromosome. Equal expression of X-chromosome genes in both sexes is ensured by
In mammals, females have two X chromosomes and males have one X chromosome. Equal expression of X-chromosome genes in both sexes is ensured by
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Dosage compensation = Equal gene output from X chromosomes in both sexes.
Inactivation of one X in females achieves this balance.
Updated On: Dec 5, 2025
- Dosage compensation
- Histone code
- RNA silencing
- Heterochromatin formation
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The Correct Option is A
Solution and Explanation
Step 1: Recall the concept.
Dosage compensation ensures that the expression of X-linked genes is balanced between males (XY) and females (XX).
Step 2: Mechanism in mammals.
In female mammals, one X chromosome is randomly inactivated during early embryonic development (Lyonization), forming a Barr body.
Step 3: Conclusion.
Hence, equal expression is achieved through dosage compensation.
Dosage compensation ensures that the expression of X-linked genes is balanced between males (XY) and females (XX).
Step 2: Mechanism in mammals.
In female mammals, one X chromosome is randomly inactivated during early embryonic development (Lyonization), forming a Barr body.
Step 3: Conclusion.
Hence, equal expression is achieved through dosage compensation.
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