Step 1: Use the condition that \( z_3 \) is the midpoint of \( z_1 \) and \( z_2 \).
The midpoint formula for complex numbers is:
\[
z_3 = \frac{z_1 + z_2}{2}
\]
Substitute the values of \( z_1 \) and \( z_2 \):
\[
z_3 = \frac{(2 + 3i) + (4 - 5i)}{2} = \frac{6 - 2i}{2} = 3 - i
\]
So, \( z_3 = 3 - i \).
Step 2: Substitute \( z_3 \) into the given equation \( 5z_1 + xz_2 + yz_3 = 0 \).
Substitute \( z_1 = 2 + 3i \), \( z_2 = 4 - 5i \), and \( z_3 = 3 - i \) into the equation:
\[
5(2 + 3i) + x(4 - 5i) + y(3 - i) = 0
\]
This simplifies to:
\[
(10 + 15i) + x(4 - 5i) + y(3 - i) = 0
\]
Expanding the terms:
\[
10 + 15i + 4x - 5xi + 3y - yi = 0
\]
Combine real and imaginary parts:
\[
(10 + 4x + 3y) + (15 - 5x - y)i = 0
\]
Step 3: Solve for \( x \) and \( y \).
For the equation to be true, both the real and imaginary parts must be zero. This gives us the system of equations:
\[
10 + 4x + 3y = 0 \quad \text{(real part)}
\]
\[
15 - 5x - y = 0 \quad \text{(imaginary part)}
\]
Step 4: Solve the system of equations.
From the second equation, solve for \( y \):
\[
y = 15 - 5x
\]
Substitute this into the first equation:
\[
10 + 4x + 3(15 - 5x) = 0
\]
Simplify:
\[
10 + 4x + 45 - 15x = 0
\]
\[
55 - 11x = 0
\]
\[
x = 5
\]
Now substitute \( x = 5 \) into \( y = 15 - 5x \):
\[
y = 15 - 5(5) = 15 - 25 = -10
\]
Step 5: Calculate \( x + y \).
\[
x + y = 5 + (-10) = -5
\]
Thus, the value of \( x + y \) is \( \boxed{-5} \).