Concept:
If \(|u|\ll 1\), then using the Binomial Approximation,
\[
(1+u)^n \approx 1+nu,
\]
neglecting terms involving \(u^2\) and higher powers.
Step 1: Rewrite the given expression.
\[
\left(\frac{3x+64}{3x+8}\right)^{\frac{2}{3}}
=
\left(\frac{64\left(1+\frac{3x}{64}\right)}
{8\left(1+\frac{3x}{8}\right)}\right)^{\frac{2}{3}}.
\]
\[
=
\left[
8\cdot
\frac{1+\frac{3x}{64}}
{1+\frac{3x}{8}}
\right]^{\frac{2}{3}}.
\]
\[
=
8^{\frac{2}{3}}
\left(
\frac{1+\frac{3x}{64}}
{1+\frac{3x}{8}}
\right)^{\frac{2}{3}}.
\]
Since
\[
8^{\frac{2}{3}}=4,
\]
we get
\[
=4
\left(
\frac{1+\frac{3x}{64}}
{1+\frac{3x}{8}}
\right)^{\frac{2}{3}}.
\]
Step 2: Simplify the fraction inside the bracket.
Using
\[
\frac{1+a}{1+b}\approx 1+a-b,
\]
we obtain
\[
\frac{1+\frac{3x}{64}}
{1+\frac{3x}{8}}
\approx
1+\frac{3x}{64}-\frac{3x}{8}.
\]
\[
=
1-\frac{21x}{64}.
\]
Therefore,
\[
\left(\frac{3x+64}{3x+8}\right)^{\frac{2}{3}}
\approx
4\left(1-\frac{21x}{64}\right)^{\frac{2}{3}}.
\]
Step 3: Apply the binomial approximation.
Using
\[
(1+u)^n\approx 1+nu,
\]
with
\[
u=-\frac{21x}{64},
\qquad
n=\frac23,
\]
we get
\[
\left(1-\frac{21x}{64}\right)^{\frac23}
\approx
1+\frac23\left(-\frac{21x}{64}\right).
\]
\[
=
1-\frac{7x}{32}.
\]
Hence,
\[
\left(\frac{3x+64}{3x+8}\right)^{\frac{2}{3}}
\approx
4\left(1-\frac{7x}{32}\right).
\]
\[
=
4-\frac{28x}{32}.
\]
\[
=
4-\frac{7x}{8}.
\]
Step 4: Write the final answer.
\[
\boxed{4-\frac{7x}{8}}
\]