Question

Identify ``X'' name of enzyme; and ``Y'' enzyme class number by observing the reaction given below:
\[ \text{Glutamic acid} + NH_3 + \text{ATP} \xrightarrow{X} \text{Glutamine} + \text{ADP} + \text{iP} \]

• A. X - Glutamine oxidase, Y - 2
• B. X - Glutamine synthetase, Y - 6
• C. X - Glutamine reductase, Y - 4
• D. X - Glutamine carboxylase, Y - 5

Hint:

Use the mnemonic {OTH LIL} to remember enzyme classes: Oxidoreductases, Transferases, Hydrolases, Lyases, Isomerases, Ligases.

Answer 1

The Correct Option is B

Step 1: Interpreting the reaction:
The given reaction represents the conversion of glutamic acid into glutamine. In this process, ammonia ($NH_3$) is incorporated, and energy is supplied through the hydrolysis of ATP into ADP and inorganic phosphate ($iP$).

Step 2: Determining enzyme X:
Reactions that involve the formation of a new bond between molecules using energy derived from ATP are catalyzed by enzymes known as synthetases.
In this specific case, the enzyme responsible for converting glutamate to glutamine is glutamine synthetase.

Step 3: Identifying enzyme class Y:
According to the IUBMB classification, enzymes are divided into six major classes:

• Oxidoreductases
• Transferases
• Hydrolases
• Lyases
• Isomerases
• Ligases

Since this reaction involves the joining of two molecules with the help of ATP, the enzyme belongs to the Ligases category, which corresponds to Class 6.

Step 4: Conclusion:
Thus, enzyme X is glutamine synthetase, and enzyme class Y is Class 6 (Ligases).