Step 1: Identifying the pattern in the sequence.
The differences between consecutive terms are:
\[
6 - 5 = 1, \quad 15 - 6 = 9, \quad 89 - 15 = 74, \quad 170 - 89 = 81, \quad 291 - 170 = 121.
\]
There seems to be a growing pattern in the differences.
The second differences are:
\[
9 - 1 = 8, \quad 74 - 9 = 65, \quad 81 - 74 = 7, \quad 121 - 81 = 40.
\]
This indicates that the missing number is \( 40 \).
Thus, the correct answer is \( 40 \).