Question

Given below are two statements
Statement I: HCG is a synthetic hormone
Statement II: Ovaprim is a synthetic hormone
In light of the above statements, choose the correct answer from the options given below

• A. Statement I and Statement II are true
• B. Statement I and Statement II are false
• C. Statement I is true and Statement II is false
• D. Statement I is false and Statement II is true

Hint:

HCG = Natural (extracted from human urine).
Ovaprim/Ovatide/Spawnpro = Synthetic (GnRH analogue + Domperidone).
Synthetic agents are generally preferred today due to standardized potency and lack of immunological response.

Answer 1

The Correct Option is D

Step 1: Understanding the Question:
The question evaluates the origin (natural vs. synthetic) of two commonly used inducing agents in fish hatcheries: Human Chorionic Gonadotropin (HCG) and Ovaprim.
Detailed Explanation:

• Human Chorionic Gonadotropin (HCG): HCG is a glycoprotein hormone produced by the placenta during pregnancy. For use in aquaculture, it is purified and extracted from the urine of pregnant women. Since it is a biological product of animal origin, it is considered a natural hormone, not synthetic. Therefore, Statement I is false.

• Ovaprim: Ovaprim is a commercially available inducing agent used for spawning. It is a synthetic preparation containing a Salmon Gonadotropin-Releasing Hormone analogue (sGnRH-a) combined with a dopamine antagonist (Domperidone). Because its active components are manufactured chemically, it is categorized as a synthetic hormone preparation. Therefore, Statement II is true.

• Comparison: HCG acts directly on the gonads (bypassing the pituitary), whereas Ovaprim (GnRH analogue) acts on the fish's own pituitary to release endogenous gonadotropins.

Step 3: Final Answer:
Statement I is false because HCG is a natural hormone, and Statement II is true because Ovaprim is a synthetic formulation.