Question

Given below are two statements: One is labelled as Assertion A and the other is labelled as Reason R.
Assertion A: During the transportation of gases, about 20-25 percent of \(CO_2\) is carried by Haemoglobin as carbamino-haemoglobin.
Reason R: This binding is related to high p \(CO_2\) and low p \(O_2\) in tissues.
In the light of the above statements, choose the correct answer from the options given below

• A. A is true but R is false
• B. A is false but R is true
• C. Both A and R are true and R is the correct explanation of A.
• D. Both A and R are true but R is NOT the correct explanation of A.

Answer 1

The Correct Option is C

To determine the correct answer, we need to evaluate both the assertion and the reason provided in the question.

1. Understanding the Assertion A: The statement says that during the transportation of gases in the blood, about 20-25% of carbon dioxide (\(CO_2\)) is carried by hemoglobin as carbamino-hemoglobin. This is a true statement. In the human body, carbon dioxide is transported from the tissues to the lungs in three forms: dissolved in plasma, as bicarbonate ions, and bound to hemoglobin as carbamino-hemoglobin. Approximately 20-25% of carbon dioxide is indeed transported in this way.
2. Understanding the Reason R: The reason given is that the binding of carbon dioxide to hemoglobin is related to high partial pressure of carbon dioxide (p \(CO_2\)) and low partial pressure of oxygen (p \(O_2\)) in the tissues. This statement is also true. In tissues, the partial pressure of \(CO_2\) is high and that of \(O_2\) is low, enhancing the formation of carbamino-hemoglobin. This is in accordance with the physiological principles governing gas transport in the body.
3. Evaluating the Relationship: Both Assertion A and Reason R are true, and Reason R is the correct explanation of Assertion A. The conditions described in Reason R directly explain why \(CO_2\) binds to hemoglobin in the tissues, thus justifying the assertion about the percentage of carbon dioxide transported as carbamino-hemoglobin.

Conclusion: The correct answer is: Both A and R are true and R is the correct explanation of A.