Concept:
Shortest distance between two skew lines is:
\[
d=
\frac{|(\vec a_2-\vec a_1)\cdot(\vec b_1\times\vec b_2)|}
{|\vec b_1\times\vec b_2|}
\]
where:
• \(\vec a_1,\vec a_2\) are points on the lines
• \(\vec b_1,\vec b_2\) are direction vectors
Step 1: Identify position and direction vectors
From first line:
\[
\vec a_1=(1,2,1)
\]
\[
\vec b_1=(1,-1,1)
\]
From second line:
\[
\vec a_2=(2,-1,-1)
\]
\[
\vec b_2=(2,1,2)
\]
Step 2: Find cross product of direction vectors
\[
\vec b_1\times\vec b_2=
\begin{vmatrix}
\hat i&\hat j&\hat k\\
1&-1& 1\\
2& 1& 2
\end{vmatrix}
\]
Expanding determinant:
\[
=
\hat i((-1)(2)-(1)(1))
-\hat j((1)(2)-(1)(2))
+\hat k((1)(1)-(-1)(2))
\]
\[
=
\hat i(-2-1)-\hat j(2-2)+\hat k(1+2)
\]
\[
=-3\hat i+0\hat j+3\hat k
\]
Thus:
\[
\vec b_1\times\vec b_2=(-3,0,3)
\]
Magnitude:
\[
|\vec b_1\times\vec b_2|
=
\sqrt{(-3)^2+0^2+3^2}
\]
\[
=\sqrt{9+9}
\]
\[
=\sqrt{18}
\]
Step 3: Find connecting vector
\[
\vec a_2-\vec a_1
=(2-1,-1-2,-1-1)
\]
\[
=(1,-3,-2)
\]
Step 4: Apply shortest distance formula
\[
d=
\frac{|(1,-3,-2)\cdot(-3,0,3)|}
{\sqrt{18}}
\]
Compute dot product:
\[
=(1)(-3)+(-3)(0)+(-2)(3)
\]
\[
=-3+0-6
\]
\[
=-9
\]
Taking modulus:
\[
|{-9}|=9
\]
Thus:
\[
d=\frac{9}{\sqrt{18}}
\]
Rationalized form:
\[
=\frac{9}{\sqrt{54}}
\]
Final Answer:
\[
\boxed{\frac{9}{\sqrt{54}}}
\]