Question:
Epileptic (epileptogenic) potential is present in which of the following inhalational anaesthetic agents?
Epileptic (epileptogenic) potential is present in which of the following inhalational anaesthetic agents?
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Think of the volatile agent linked to EEG spikes during hyperventilation and fast mask induction.
Updated On: Jun 24, 2026
- Desflurane
- Halothane
- Sevoflurane
- Ether
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The Correct Option is C
Solution and Explanation
Step 1: The question asks which inhalational agent is associated with epileptiform EEG activity (seizure-like spikes), i.e. has epileptogenic potential.
Step 2: Among the listed agents, Sevoflurane is well documented to produce epileptiform EEG discharges, especially at high concentrations, during rapid inhalational induction, and with hypocapnia (hyperventilation). For this reason caution is advised in patients with a history of seizures.
Step 3: Reviewing the other options: Desflurane and Halothane are not associated with epileptiform activity. Ether is a classical anaesthetic without notable epileptogenic action; the most epileptogenic volatile agent historically is enflurane, but it is not in the option list.
Step 4: Therefore, among the given choices, Sevoflurane is the agent with epileptic potential.
Conclusion: The correct answer is Sevoflurane (option 3), matching the printed key.
Step 2: Among the listed agents, Sevoflurane is well documented to produce epileptiform EEG discharges, especially at high concentrations, during rapid inhalational induction, and with hypocapnia (hyperventilation). For this reason caution is advised in patients with a history of seizures.
Step 3: Reviewing the other options: Desflurane and Halothane are not associated with epileptiform activity. Ether is a classical anaesthetic without notable epileptogenic action; the most epileptogenic volatile agent historically is enflurane, but it is not in the option list.
Step 4: Therefore, among the given choices, Sevoflurane is the agent with epileptic potential.
Conclusion: The correct answer is Sevoflurane (option 3), matching the printed key.
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