Question:
Dystrophic calcification is seen in:
Dystrophic calcification is seen in:
Show Hint
Dystrophic calcification occurs in damaged tissue with normal blood calcium; metastatic calcification needs high blood calcium.
Updated On: Jul 8, 2026
- Rickets
- Hyperparathyroidism
- Atheromatous plaque
- Vitamin A intoxication
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Understanding the Question:
We need to identify which of the given conditions shows dystrophic calcification, that is calcium deposition in damaged or dead tissue while blood calcium levels stay normal.
Step 2: Key Formula or Approach:
Calcification is split into two types. Dystrophic calcification happens in areas of cell injury, necrosis, or degeneration, with normal serum calcium, common examples are atheromatous plaques, caseous tuberculous necrosis, fat necrosis, and damaged heart valves. Metastatic calcification happens in normal tissue because the blood calcium or phosphate level is raised, common causes are hyperparathyroidism, vitamin D or vitamin A excess, and conditions like rickets related bone and mineral disturbances.
Step 3: Detailed Explanation:
Rickets is a disorder of bone mineralisation from vitamin D deficiency, when it is treated or when there is an associated disturbance, it is linked with abnormal calcium and phosphate handling, and calcification here follows the metastatic pattern of raised mineral levels, not local tissue death.
Hyperparathyroidism raises blood calcium directly by increasing bone resorption, and this high calcium can deposit in normal tissues such as kidney and lung, which is metastatic calcification.
Atheromatous plaque contains areas of lipid deposition, cell death, and degeneration in the arterial wall, calcium salts deposit locally in this damaged tissue while the blood calcium level stays normal, this is the classic example of dystrophic calcification.
Vitamin A intoxication can raise blood calcium and contribute to metastatic calcification, it is not an example of local dystrophic change.
Step 4: Final Answer:
Dystrophic calcification, calcification in locally damaged tissue with a normal blood calcium level, is seen in atheromatous plaque.
We need to identify which of the given conditions shows dystrophic calcification, that is calcium deposition in damaged or dead tissue while blood calcium levels stay normal.
Step 2: Key Formula or Approach:
Calcification is split into two types. Dystrophic calcification happens in areas of cell injury, necrosis, or degeneration, with normal serum calcium, common examples are atheromatous plaques, caseous tuberculous necrosis, fat necrosis, and damaged heart valves. Metastatic calcification happens in normal tissue because the blood calcium or phosphate level is raised, common causes are hyperparathyroidism, vitamin D or vitamin A excess, and conditions like rickets related bone and mineral disturbances.
Step 3: Detailed Explanation:
Rickets is a disorder of bone mineralisation from vitamin D deficiency, when it is treated or when there is an associated disturbance, it is linked with abnormal calcium and phosphate handling, and calcification here follows the metastatic pattern of raised mineral levels, not local tissue death.
Hyperparathyroidism raises blood calcium directly by increasing bone resorption, and this high calcium can deposit in normal tissues such as kidney and lung, which is metastatic calcification.
Atheromatous plaque contains areas of lipid deposition, cell death, and degeneration in the arterial wall, calcium salts deposit locally in this damaged tissue while the blood calcium level stays normal, this is the classic example of dystrophic calcification.
Vitamin A intoxication can raise blood calcium and contribute to metastatic calcification, it is not an example of local dystrophic change.
Step 4: Final Answer:
Dystrophic calcification, calcification in locally damaged tissue with a normal blood calcium level, is seen in atheromatous plaque.
Was this answer helpful?
0
0
Top NEET PG Pathology Questions
- Which of the following is true regarding the Mendelian mode of inheritance?
- A child presents with intermittent jaundice and splenomegaly. There is a history of similar complaints in the elder brother. Peripheral smear shows the following finding. How will you investigate this condition?
- An African child is found to have a mass in the jaw. A biopsy of the mass was done, and it appears as shown in the image below. The child also had a translocation of t(8;14). What is the probable diagnosis?
- A child presented to the hospital with cola-colored urine, hypertension, and puffiness of eyes. Laboratory investigations were done, and creatinine was 2.5 mg/dL. Treatment was started, and despite treatment, the patient did not improve for the next 3 weeks. The creatinine value increased to 4.5 mg/dL. Which among the following electron microscopic findings will be seen in this patient ?
- A patient was transfused 4 units of blood 2 hours ago, and now she complains of chest discomfort. X-ray shows bilateral fissural thickening. Which of the following is the most probable cause ?
View More Questions
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions