Question:

During which stage does the synaptonemal complex dissolve?

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Use this simple mnemonic to remember the sequence of Prophase I stages and their key events:
- Leptotene: Condensation.
- Zygotene: Synapsis (complex forms).
- Pachytene: Crossing over.
- Diplotene: Dissolution of complex (chiasmata appear).
- Diakinesis: Terminalisation of chiasmata.
Updated On: Jun 3, 2026
  • Leptotene
  • Pachytene
  • Diplotene
  • Zygotene
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Question:
The question asks to identify the specific sub-stage of Prophase I of Meiosis I during which the protein structure known as the synaptonemal complex undergoes dissolution.

Step 2: Detailed Explanation:


• Prophase I of Meiosis I is divided into five sequential stages based on chromosomal behavior: Leptotene, Zygotene, Pachytene, Diplotene, and Diakinesis.

• During the Leptotene stage, chromatin fibers condense into distinct chromosomes.

• During the Zygotene stage, homologous chromosomes begin to pair up in a highly specific alignment called synapsis. This pairing is facilitated by the assembly of a ladder-like protein structure called the synaptonemal complex.

• During the Pachytene stage, crossing over (genetic recombination) takes place between non-sister chromatids of the synapsed homologous chromosomes, mediated by recombination nodules.

• The beginning of the Diplotene stage is characterized by the dissolution and breakdown of this synaptonemal complex.

• As the synaptonemal complex dissolves, the homologous chromosomes begin to separate from one another.

• However, they remain temporarily held together at the specific sites where crossing over occurred. These persistent, X-shaped points of contact are known as chiasmata, which become clearly visible during Diplotene.

Step 3: Final Answer:

The synaptonemal complex dissolves during the Diplotene stage of Prophase I.
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