Question

During which phase of mitosis do the centromeres split and chromatids move to opposite poles?

• A. Prophase
• B. Metaphase
• C. Anaphase
• D. Telophase

Hint:

*Remember:* "Anaphase = Apart." It’s when the chromatids move apart to opposite poles.

Answer 1

The Correct Option is C

To solve the problem, we need to understand the stages of mitosis and identify the phase during which the centromeres split and chromatids move to opposite poles.

1. Understanding Mitosis:

Mitosis is a process by which a cell divides to produce two identical daughter cells. It ensures that each daughter cell receives an exact copy of the parent cell's DNA. Mitosis has several phases:

• Prophase: Chromosomes condense, spindle fibers form.
• Metaphase: Chromosomes align at the cell's equator.
• Anaphase: Centromeres split and sister chromatids are pulled apart toward opposite poles.
• Telophase: Chromatids reach the poles, nuclear membranes reform.

2. Key Event in Question:

The phase when centromeres split and chromatids move to opposite poles is anaphase.

3. Why Anaphase?

- In anaphase, the paired sister chromatids separate at their centromeres.
- The separated chromatids, now individual chromosomes, are pulled by spindle fibers to opposite ends of the cell.
- This separation ensures that each new cell will receive one copy of each chromosome.

Final Answer:

The centromeres split and chromatids move to opposite poles during anaphase of mitosis.