Question:

Correct sequential steps of Malaria spread-

• [(K)] Infected female Anopheles bites a healthy human.

• [(L)] Parasite invades the liver.

• [(M)] Fever, Shivering and feeling cold.

• [(N)] Parasite invades the red blood cells.

• [(O)] New mosquito gets infected by blood of patient.
Choose the correct option-

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Malaria flow: Mosquito bite → Liver → RBC → Symptoms → New mosquito.
Updated On: Jun 11, 2026
  • A. $ \text{K} \rightarrow \text{M} \rightarrow \text{L} \rightarrow \text{N} \rightarrow \text{O} $
  • B. $ \text{K} \rightarrow \text{N} \rightarrow \text{M} \rightarrow \text{L} \rightarrow \text{O} $
  • C. $ \text{K} \rightarrow \text{L} \rightarrow \text{N} \rightarrow \text{M} \rightarrow \text{O} $
  • D. $ \text{K} \rightarrow \text{L} \rightarrow \text{M} \rightarrow \text{N} \rightarrow \text{O} $
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The Correct Option is C

Solution and Explanation

Concept: Malaria is caused by the protozoan parasite Plasmodium and is transmitted through the bite of an infected female Anopheles mosquito. Its life cycle includes stages in both the human liver and red blood cells, followed by transmission back to mosquitoes.

Step 1: Infection begins

• (K) The cycle starts when an infected female Anopheles mosquito bites a healthy human and injects sporozoites.

Step 2: Liver stage

• (L) Sporozoites travel to the liver and multiply inside hepatocytes.

Step 3: Blood stage

• (N) Merozoites are released and invade red blood cells.

Step 4: Symptom stage

• (M) Rupture of RBCs releases toxins causing fever, chills, and shivering.

Step 5: Transmission stage

• (O) A new mosquito bites the infected person and becomes infected.

Final sequence: \[ \text{K} \rightarrow \text{L} \rightarrow \text{N} \rightarrow \text{M} \rightarrow \text{O} \]
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