Question:
Chromosome involved in myotonic dystrophy is
Chromosome involved in myotonic dystrophy is
Updated On: Jul 12, 2025
- Chromosome 19
- Chromosome 20
- Chromosome 21
- Chromosome 22
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The Correct Option is A
Solution and Explanation
Myotonic dystrophy is a genetic disorder characterized by progressive muscle wasting and weakness. The condition is caused by mutations in specific genes. The gene responsible for myotonic dystrophy type 1, which is the most common form, is the DMPK gene.
This gene is located on Chromosome 19, specifically at the 19q13.32 region. Mutations in this gene, often involving an abnormal expansion of a CTG trinucleotide repeat, lead to the symptoms associated with myotonic dystrophy.
Thus, when considering the options provided:
| Options | Description |
|---|---|
| Chromosome 19 | Correct - Contains the DMPK gene linked to Myotonic Dystrophy. |
| Chromosome 20 | Incorrect |
| Chromosome 21 | Incorrect |
| Chromosome 22 | Incorrect |
In summary, the chromosome involved in myotonic dystrophy is Chromosome 19, due to the location of the DMPK gene.
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