Concept:
Every endocrine gland secretes specific hormones. To identify a mismatched pair, each gland-hormone combination must be verified.
Step 1: Check Leydig cells -- Testosterone.
Leydig cells are present in testes.
They secrete:
\[
\boxed{\text{Testosterone}}
\]
Hence this pair is correct.
Step 2: Check Corpus luteum -- Progesterone.
Corpus luteum develops after ovulation.
It secretes:
\[
\boxed{\text{Progesterone}}
\]
Hence this pair is correct.
Step 3: Check Pancreas -- Glucagon.
Alpha cells of pancreas secrete:
\[
\boxed{\text{Glucagon}}
\]
Therefore this pair is correct.
Step 4: Check Pineal gland -- Calcitonin.
Pineal gland secretes:
\[
\boxed{\text{Melatonin}}
\]
Calcitonin is secreted by:
\[
\boxed{\text{Thyroid gland}}
\]
Therefore this pair is incorrect.
Step 5: Identify the mismatched pair.
\[
\boxed{\text{Pineal gland -- Calcitonin}}
\]
Hence,
\[
\boxed{\text{Option (D)}}
\]