Question

Choose the correct sequence of enzymes involved in the preparatory phase of glycolysis:

• A. A, C, D, B and E
• B. A, C, B, D and E
• C. B, A, C, E and D
• D. D, C, A, B and E

Hint:

Remember: Kinase $\to$ Isomerase $\to$ Kinase $\to$ Aldolase $\to$ Isomerase (K-I-K-A-I).

Answer 1

The Correct Option is B

Step 1: Concept
The preparatory phase of glycolysis (first 5 steps) consumes ATP to prime glucose. Step 2--3: Analysis
Hexokinase (A) converts glucose to Glucose-6-P. Phospho-hexose isomerase (C) converts it to Fructose-6-P. Phosphofructokinase-1 (B) creates Fructose-1,6-bisP. Aldolase (D) cleaves it. Triose-phosphate isomerase (E) interconverts the products.

Step 4: Conclusion
The order is A $\to$ C $\to$ B $\to$ D $\to$ E.

Final Answer: (B)