Step 1: Understanding the Question:
The question asks us to arrange the anatomical structures of the human olfactory (smell) system from the outermost external structures to the innermost brain-based structures.
Step 2: Detailed Explanation:
• D. Nasal Cavity: The outermost part of the system is the nasal cavity, through which airborne chemical odorants enter during inhalation.
• C. Cilia: Within the nasal cavity, the odorant molecules bind to the hair-like cilia that project into the olfactory mucosa.
• E. Receptor cells: These cilia are the specialized dendrites of the olfactory receptor cells (bipolar neurons) located in the olfactory epithelium.
• B. Nerve fibre: The axons of these receptor cells gather together to form olfactory nerve fibers, which pass upward through the tiny openings of the cribriform plate.
• A. Olfactory bulb: These nerve fibers terminate and synapse in the olfactory bulb, which is the innermost brain structure of this sequence, located directly beneath the frontal lobe.
• This anatomical progression from outside to inside corresponds to the sequence: D $\rightarrow$ C $\rightarrow$ E $\rightarrow$ B $\rightarrow$ A.
Step 3: Final Answer:
The correct anatomical order from outer to inner structures of the olfactory system is D - C - E - B - A.