Concept:
Drugs act by interacting with receptors. Some drugs activate receptors, while some drugs block receptors.
Step 1: An agonist binds to a receptor and produces a response.
Step 2: An antagonist binds to a receptor but does not activate it.
Step 3: It prevents the agonist or natural ligand from producing its effect.
Step 4: Thus, an antagonist blocks receptor response.
Step 5: Therefore, the correct answer is blocks receptor response.
\[
\boxed{\text{Blocks receptor response}}
\]