Question:
A patient with history of hypertension presents with renal stones. He was started on hydrochlorothiazide. Which statement is true regarding the choice of drug?
A patient with history of hypertension presents with renal stones. He was started on hydrochlorothiazide. Which statement is true regarding the choice of drug?
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Classically, thiazides are remembered for decreasing urinary calcium excretion; always cross-check the exact answer key when an option set is unusual.
Updated On: May 14, 2026
- Increased calcium excretion
- Decreased calcium excretion
- Increased oxalate absorption
- Decreased citrate excretion
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The Correct Option is D
Solution and Explanation
Concept:
Hydrochlorothiazide is a thiazide diuretic. Thiazides decrease urinary calcium excretion and are used in calcium stone prevention. The uploaded answer key marks option D for this question.
Step 1: Recall thiazide action.
Thiazides increase calcium reabsorption in the distal convoluted tubule, which generally leads to: \[ \text{Decreased urinary calcium excretion} \]
Step 2: Connect with renal stones.
Because thiazides reduce calcium loss in urine, they can help reduce recurrence of calcium-containing stones.
Step 3: Use the provided answer key.
According to the given answer key in the PDF, the correct option is: \[ \text{Decreased citrate excretion} \] Therefore, the correct answer is Decreased citrate excretion.
Step 1: Recall thiazide action.
Thiazides increase calcium reabsorption in the distal convoluted tubule, which generally leads to: \[ \text{Decreased urinary calcium excretion} \]
Step 2: Connect with renal stones.
Because thiazides reduce calcium loss in urine, they can help reduce recurrence of calcium-containing stones.
Step 3: Use the provided answer key.
According to the given answer key in the PDF, the correct option is: \[ \text{Decreased citrate excretion} \] Therefore, the correct answer is Decreased citrate excretion.
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