Question:

A newborn presents with sudden onset bilious vomiting shortly after birth. Abdominal X-ray shows a double-bubble sign, but unlike classic duodenal atresia, there is also a gasless abdomen, raising concern for a surgical emergency. What is the most likely diagnosis?

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Bilious vomiting in a neonate is Midgut Volvulus until proven otherwise by an Upper GI contrast study.
Time is bowel: Volvulus requires immediate emergent laparotomy (Ladd's procedure) to prevent complete midgut necrosis.
Updated On: Sep 3, 2026
  • Duodenal atresia
  • Jejunal atresia
  • Malrotation with midgut volvulus
  • Meconium ileus
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The Correct Option is C

Solution and Explanation

Concept:
The clinical scenario presents a newborn with sudden bilious vomiting and a specific variation of the "double-bubble" sign on an abdominal radiograph.
The clinician must recognize the critical difference between a congenital atresia and an acute vascular catastrophe of the bowel.
Explanation:
• Sudden onset bilious (green) vomiting in a neonate is the cardinal sign of an obstruction distal to the ampulla of Vater, and must be considered Malrotation with midgut volvulus until proven otherwise.

• A classic "double-bubble" sign on X-ray indicates an obstruction at the level of the duodenum (the two bubbles represent air in the stomach and the dilated proximal duodenum).

• While Duodenal Atresia is the most common cause of a double-bubble, it is a static, congenital condition usually presenting immediately on day one, and crucially, usually lacks any distal gas entirely from birth.

• However, if a neonate suddenly develops bilious vomiting after initially being well, and the X-ray shows a double-bubble but now with an acutely gasless distal abdomen, it indicates an acute, complete, catastrophic twist of the bowel.

• This twist is a Midgut Volvulus secondary to intestinal malrotation.

• The volvulus cuts off the superior mesenteric artery (SMA) blood supply to the entire midgut, causing rapid, irreversible bowel necrosis and death if not surgically untwisted (Ladd's procedure) within hours.

• Because it is an acute vascular emergency, this diagnosis must take precedence over static atresias when sudden clinical deterioration occurs.
Final Answer:
Sudden bilious vomiting with a double-bubble and gasless distal abdomen indicates an acute, life-threatening obstruction caused by Malrotation with midgut volvulus.
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