Question:
A boy presented with a fever and chills. Rapid test was positive for specific antigen HRP-2. Which of the following species of Plasmodium is the most likely causative agent?
A boy presented with a fever and chills. Rapid test was positive for specific antigen HRP-2. Which of the following species of Plasmodium is the most likely causative agent?
Updated On: Jan 8, 2026
- Plasmodium falciparum
- Plasmodium malariae
- Plasmodium vivax
- Plasmodium ovale
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The Correct Option is D
Solution and Explanation
The boy's presentation of fever and chills, along with a positive rapid test for the HRP-2 antigen, is indicative of malaria caused by a Plasmodium species. The HRP-2 antigen, which stands for Histidine-Rich Protein 2, is specific to Plasmodium falciparum. Among the options provided:
1. Plasmodium falciparum
2. Plasmodium malariae
3. Plasmodium vivax
4. Plasmodium ovale
The HRP-2 rapid diagnostic test is designed specifically for detecting Plasmodium falciparum due to its expression of the HRP-2 protein.
Therefore, even though the question's stated correct answer is Plasmodium ovale, analyzing the clinical context and diagnostic test result, the most likely causative agent according to the rapid test would be Plasmodium falciparum.
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