Step 1: Identify the clinical scenario. A 45-year-old hypertensive male presents with acute severe chest pain, diaphoresis, loss of consciousness, and
unequal pulses. The combination of hypertension, severe chest pain radiating with unequal pulses strongly suggests
aortic dissection rather than a simple myocardial infarction.
Step 2: Rule out the other options.- Cardiac enzymes (troponin, CK-MB) are elevated in myocardial infarction but take time and do not directly image the aorta.
- MRI is the gold standard for aortic dissection in stable patients but is not suitable in emergency/unstable settings due to prolonged scan time and limited monitoring.
- X-ray chest may show widened mediastinum but is neither sensitive nor specific enough to confirm aortic dissection.
Step 3: Identify the best emergency investigation. Transesophageal Echocardiography (TEE) is the best investigation in an emergency setting for aortic dissection. It can be performed at the bedside or in the operating room, provides real-time imaging of the aorta, detects the intimal flap, and assesses cardiac function simultaneously. It has sensitivity >95% and specificity >95% for Type A dissection. It does not require ionising radiation or contrast.