Question:
A 45-year-old male presents with discomfort in his joints. Synovial fluid aspiration reveals rhomboid-shaped positively birefringent crystals under polarized light microscopy. What is the most likely diagnosis?
A 45-year-old male presents with discomfort in his joints. Synovial fluid aspiration reveals rhomboid-shaped positively birefringent crystals under polarized light microscopy. What is the most likely diagnosis?
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Pseudogout = rhomboid, positively birefringent crystals. Gout = needle-shaped, negatively birefringent crystals.
Updated On: May 14, 2026
- Gout
- Rheumatoid arthritis
- Osteoarthritis
- Pseudogout
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Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Concept:
Pseudogout is caused by calcium pyrophosphate crystal deposition. The crystals are rhomboid-shaped and positively birefringent under polarized light.
Step 1: Identify the crystal shape.
The crystals are: \[ \text{Rhomboid-shaped} \]
Step 2: Identify birefringence.
Positive birefringence is typical of calcium pyrophosphate crystals.
Step 3: Select diagnosis.
Calcium pyrophosphate deposition disease is also called: \[ \text{Pseudogout} \] Therefore, the correct answer is Pseudogout.
Step 1: Identify the crystal shape.
The crystals are: \[ \text{Rhomboid-shaped} \]
Step 2: Identify birefringence.
Positive birefringence is typical of calcium pyrophosphate crystals.
Step 3: Select diagnosis.
Calcium pyrophosphate deposition disease is also called: \[ \text{Pseudogout} \] Therefore, the correct answer is Pseudogout.
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