List of top Questions asked in ICSE- 2026

Shama complained of severe itching in certain parts of her body where patches as shown below appeared on her skin. Write the biological name of the causative agent responsible for her condition. 

 

The enzyme polynucleotide phosphorylase helps the in-vitro synthesis of RNA. Name the scientist who discovered this enzyme.
‘Homework is a necessary evil.’ Express your views either for or against this statement.
Expand the abbreviation IUI.
Name the autoimmune disorder that affects the skeletal muscles in humans.
In a garden pea plant, the flowers are in axial (A) position. Find out the proportion of flowers in terminal position (a), if a cross is made between two heterozygous plants.
Given below are two statements marked Assertion and Reason.
Assertion: RNAi technique is applied to plants and animals to protect them from pest infestation.
Reason: This technique inhibits the expression of certain genes in pests.
The left hind limb of a person was swollen like elephant’s limb. Which one of the following was MOST likely the cause of swelling?
Choose the components that are required for the proper functioning of DNA polymerase enzyme.
(P) DNA template
(Q) A DNA primer
(R) An RNA primer
(S) Four different dNTPs
In a particular plant with bilobed dithecous anther, there were 50 Pollen Mother Cells. Only 25% could develop their pollen tubes. Calculate the number of pollen grains that would proceed for fertilisation.
A farmer notices that the leaves of his cabbage plants are curling up because of heavy infestation of aphids. Suggest one ecofriendly method to control their spread in the cabbage plants.
There were 770 frogs in a pond. 70 of them died within a month. Calculate the death rate of the population of frogs in the pond.
Meenu is suffering from a genetic disorder in which phenylpyruvic acid and its metabolites accumulate in blood. It causes impairment of nervous tissues. Which enzyme deficiency has caused this disorder in Meenu?
A scientist isolates a second restriction endonuclease from the strain DC3 of Helicobacter pyogenes. What would the scientist name it using the standard naming technique of restriction enzyme?
If the number of chromosomes in the cells of the calyx is 16, how many chromosomes will be formed in the endosperm after double fertilisation?

Observe the relation between the first two words and complete the analogy. 
Dengue: Aedes :: Plague: __________
 

Zara is suffering from cough and has bluish lips. Her mucus is mixed with blood. What is the biological name of the causative organism responsible for Zara’s condition?
Explain the role of Restriction Endonucleases and Ligases in recombinant DNA technology.
Discuss the steps involved in Plant Breeding for developing disease-resistant varieties.
Explain Incomplete Dominance and Co-dominance with suitable examples.
Describe the structure of a Nucleosome and the packaging of DNA.
Discuss DNA Fingerprinting steps and its forensic applications.
Differentiate between Homologous and Analogous organs with examples of divergent and convergent evolution.
Explain the life cycle of Plasmodium (Malaria) and the role of the female Anopheles mosquito.
Describe the structure of a Microsporangium and the process of Microsporogenesis.