Question:
Which receptors are blocked in Myasthenia Gravis?
Which receptors are blocked in Myasthenia Gravis?
Updated On: Jul 12, 2025
- Ach receptors
- Ca++receptors
- Na2+ receptors
- Opioid receptors
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The Correct Option is A
Solution and Explanation
Myasthenia Gravis is an autoimmune neuromuscular disorder characterized by weakness and rapid fatigue of the muscles. This condition is primarily caused by an immune response that attacks communication between the nerves and muscles, specifically at the neuromuscular junction. The primary pathology involves antibodies attacking and blocking.
- Acetylcholine (Ach) receptors are located at the postsynaptic muscle membrane at the neuromuscular junction.
The receptor blockade leads to a reduced efficacy in neuromuscular transmission, causing muscle weakness and fatigue. Thus, in Myasthenia Gravis, the synaptic transmission is impaired due to the blockage of Ach receptors, preventing the binding of acetylcholine required for muscle contraction.
| Option | Status |
|---|---|
| Ach receptors | Correct |
| Ca++ receptors | Incorrect |
| Na2+ receptors | Incorrect |
| Opioid receptors | Incorrect |
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