Question:

Which of the following substances acts as both a poison and an antidote?

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Used in gastric lavage for phosphorus poisoning yet toxic itself.
Updated On: Jun 24, 2026
  • Copper sulphate (CuSO4)
  • Mercuric chloride (HgCl2)
  • Arsenic trioxide (As2O3)
  • Thallium arsenate
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The Correct Option is A

Solution and Explanation

Step 1: The agent that is itself toxic yet is also used to treat another poisoning is copper sulphate (CuSO4).

Step 2: As a poison, ingested copper sulphate causes burning epigastric and colicky abdominal pain, vomiting, and in severe cases hemolysis, hemoglobinuria, methemoglobinemia, jaundice, pancreatitis, cramps and convulsions. Death may follow from hepatic and renal failure.

Step 3: As an antidote, copper sulphate is used in gastric lavage for phosphorus poisoning. It converts elemental phosphorus into harmless, insoluble copper phosphide and coats the particles with a film of copper, preventing further absorption.

Step 4: Mercuric chloride, arsenic trioxide and thallium arsenate are pure poisons with no antidotal role, so they are incorrect.
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