Question:
Which of the following is included in the MELD (Model for End-stage Liver Disease) score?
Which of the following is included in the MELD (Model for End-stage Liver Disease) score?
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MELD uses bilirubin, INR and creatinine; albumin belongs to Child-Pugh.
Updated On: Jun 23, 2026
- Serum creatinine
- Transaminase
- Albumin
- Alkaline phosphatase
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Verified By Collegedunia
The Correct Option is A
Solution and Explanation
Step 1: The MELD score is a validated severity score for chronic liver disease that predicts three-month mortality and is used to prioritise patients on the liver transplant waiting list (adopted by UNOS in 2002).
Step 2: The three laboratory variables in the original MELD score are serum bilirubin, serum creatinine and the INR (prothrombin time). Serum creatinine (a) is therefore correct, as it reflects the renal dysfunction (hepatorenal syndrome) that worsens prognosis in cirrhosis.
Step 3: Transaminases (b) and alkaline phosphatase (d) measure hepatocellular injury and cholestasis but are NOT part of MELD. Albumin (c) is a component of the older Child-Pugh score, not MELD.
Step 4: Hence among the options, only serum creatinine belongs to MELD, so option a is the answer.
Step 2: The three laboratory variables in the original MELD score are serum bilirubin, serum creatinine and the INR (prothrombin time). Serum creatinine (a) is therefore correct, as it reflects the renal dysfunction (hepatorenal syndrome) that worsens prognosis in cirrhosis.
Step 3: Transaminases (b) and alkaline phosphatase (d) measure hepatocellular injury and cholestasis but are NOT part of MELD. Albumin (c) is a component of the older Child-Pugh score, not MELD.
Step 4: Hence among the options, only serum creatinine belongs to MELD, so option a is the answer.
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