Question:
Which nucleus is involved in the Papez circuit?
Which nucleus is involved in the Papez circuit?
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Follow the mammillothalamic tract from the mammillary bodies to its thalamic target.
Updated On: Jun 24, 2026
- Pulvinar
- VPL nucleus
- Intralaminar nucleus
- Anterior nucleus of thalamus
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The Correct Option is D
Solution and Explanation
Step 1: The Papez circuit is the classic neural loop of the limbic system that underlies emotion and memory processing.
Step 2: Trace the pathway: hippocampus to fornix to mammillary bodies, then mammillary bodies via the mammillothalamic tract to the anterior nucleus of the thalamus.
Step 3: From the anterior nucleus of the thalamus, fibres project to the cingulate gyrus, then to the entorhinal cortex and back to the hippocampus, completing the circuit.
Step 4: Therefore the thalamic nucleus that is an integral relay in this circuit is the anterior nucleus of the thalamus. The pulvinar, VPL, and intralaminar nuclei are not part of the Papez circuit.
Conclusion: The correct answer is the anterior nucleus of the thalamus (option D), matching the printed key.
Step 2: Trace the pathway: hippocampus to fornix to mammillary bodies, then mammillary bodies via the mammillothalamic tract to the anterior nucleus of the thalamus.
Step 3: From the anterior nucleus of the thalamus, fibres project to the cingulate gyrus, then to the entorhinal cortex and back to the hippocampus, completing the circuit.
Step 4: Therefore the thalamic nucleus that is an integral relay in this circuit is the anterior nucleus of the thalamus. The pulvinar, VPL, and intralaminar nuclei are not part of the Papez circuit.
Conclusion: The correct answer is the anterior nucleus of the thalamus (option D), matching the printed key.
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