- Thermodynamic inhibitors are chemicals that shift the hydrate equilibrium curve by lowering the water activity, thereby requiring lower temperature or higher pressure for hydrate formation.
- Common thermodynamic inhibitors are salts (e.g., sodium chloride) and alcohols/glycols (e.g., ethylene glycol, methanol).
- Tetrahydrofuran (THF) is not an inhibitor but actually a hydrate former used in laboratory studies.
- Tetra n-butyl ammonium bromide is a quaternary ammonium salt that forms semi-clathrate hydrates; it is not used as a thermodynamic inhibitor.
Thus, the correct thermodynamic inhibitors are (B) and (C).