Question:
Which chemical is commonly used to fuse B cells and myeloma cells?
Which chemical is commonly used to fuse B cells and myeloma cells?
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Hybridoma production:
\[
\boxed{
\text{B cell}
+
\text{Myeloma cell}
\xrightarrow{\text{PEG}}
\text{Hybridoma}
}
\]
Hybridomas produce monoclonal antibodies.
Updated On: Jul 14, 2026
- Trypsin
- Calcium chloride
- Polyethylene glycol
- EDTA
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Recall hybridoma technology.
Hybridoma technology produces monoclonal antibodies by fusing antibody-producing B lymphocytes with immortal myeloma cells.
Step 2: Identify the fusion agent. The most commonly used chemical for cell fusion is \[ \boxed{\text{Polyethylene glycol (PEG)}.} \] Therefore, \[ \boxed{(C)} \] is the correct answer.
Step 2: Identify the fusion agent. The most commonly used chemical for cell fusion is \[ \boxed{\text{Polyethylene glycol (PEG)}.} \] Therefore, \[ \boxed{(C)} \] is the correct answer.
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